Insulin-mimetics as therapeutic adjuncts for bone regeneration

摘要

Methods of promoting bone healing or regeneration by locally administering insulin mimetic agents to patients in need thereof and new uses of insulin-mimetic compounds for accelerating bone-healing processes are disclosed. Bone injury treatment and void filler devices, products and kit suitable for local administration of insulin-mimetic agents or compositions thereof to patients in need of such treatment are also disclosed.

主权项

1. A method of promoting bone injury healing or regeneration in a patient in need thereof, comprising locally administering to the bone injury site of said patient a composition sterilized for in vivo bone administration consisting essentially of an active ingredient consisting of a therapeutically effective amount of insulin-mimetic zinc or manganese compound.