发明名称 |
PYRROLIDINE-3-YLACETIC ACID DERIVATIVE -3- |
摘要 |
A compound represented by formula (1) or a pharmaceutically acceptable salt thereof has an inhibitory effect in the fractalkine-CX3CR1 pathway:
wherein R represents a C 1-6 alkyl group unsubstituted or having 1 to 3 substituents selected from Substituent Group A, a C 3-8 cycloalkyl group unsubstituted or having 1 to 3 substituents selected from Substituent Group A, or a C 3-8 cycloalkenyl group unsubstituted or having 1 to 3 substituents selected from Substituent Group A, X represents a C 1-6 alkyl group, Y and Z are the same or different from each other and each represents a halogen atom or a C 1-6 alkyl group unsubstituted or having 1 to 3 substituents selected from Substituent Group B, n represents 0 or 1, Substituent Group A consists of halogen atoms, and Substituent Group B consists of halogen atoms. |
申请公布号 |
HK1193407(A1) |
申请公布日期 |
2016.02.19 |
申请号 |
HK20140106800 |
申请日期 |
2014.07.04 |
申请人 |
EISAI R&D MANAGEMENT CO. LTD. |
发明人 |
YOSHIDA, ICHIRO;OKABE, TADASHI;MATSUMOTO, YASUNOBU;WATANABE, NOBUHISA;OHASHI, YOSHIAKI;ONIZAWA, YUJI;HARADA, HITOSHI |
分类号 |
C07D;A61K;A61P |
主分类号 |
C07D |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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