发明名称 |
METHOD FOR DESIGNATING DISEASE RELATING TO AMOUNT OF TDP-43 EXISTING IN CELLS |
摘要 |
The present invention aims to develop and provide a method for identifying a disease associated with the abundance of TDP-43 in cells and a method for producing a TDP-43 binding inhibitor. By measuring the abundance of a measurement substance, the amount of binding between a measurement substance and TDP-43, etc. in cells obtained from a subject, it is identified whether or not the subject is suffering from a disease associated with the abundance of TDP-43 in cells. Also, a drug which can significantly reduce the binding between a measurement substance and TDP-43 is produced by adding a drug candidate substance. |
申请公布号 |
EP2821504(A4) |
申请公布日期 |
2016.02.17 |
申请号 |
EP20130755605 |
申请日期 |
2013.02.28 |
申请人 |
NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY;TOKYO METROPOLITAN UNIVERSITY;LSIP, LLC |
发明人 |
TAKAHASHI, NOBUHIRO;IZUMIKAWA, KEIICHI;ISHIKAWA, HIDEAKI;YOSHIKAWA, HARUNORI;ISOBE, TOSHIAKI;TAOKA, MASATO;NAKAYAMA, HIROSHI |
分类号 |
C12Q1/68;A61K31/7088;A61P21/04;A61P25/16;A61P25/28;C12N15/09;C40B30/06;G01N33/15;G01N33/50;G01N33/566;G01N33/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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