POTENT DUAL BRD4-KINASE INHIBITORS AS CANCER THERAPEUTICS
摘要
Disclosed herein are compounds that are inhibitors of BRD4 and their use in the treatment of cancer. Methods of screening for selective inhibitors of BRD4 are also disclosed. In certain aspects, disclosed are compounds of Formula I-IV.
申请公布号
WO2016022460(A1)
申请公布日期
2016.02.11
申请号
WO2015US43389
申请日期
2015.08.03
申请人
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
发明人
SCHÖNBRUNN, ERNST;LAWRENCE, NICHOLAS, J.;LAWRENCE, HARSHANI, R.
