Method of screening of compounds using membrane STIM1

摘要

The invention relates to the use of the fraction of the STIM1 protein localized to the plasma membrane of the cells in a method for screening candidate molecules for treating chronic lymphatic leukaemia and/or systemic lupus erythematosus. The invention also relates to a substance interacting with the fraction of the STIM1 protein localized to the plasma membrane of the cells for use as a medicinal product in the treatment of chronic lymphatic leukaemia and/or systemic lupus erythematosus, as well as to a pharmaceutical composition comprising at least one substance according to the invention.