Satiation devices and methods

摘要

A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.

主权项

1. An intestinal barrier, comprising:
an elongate polymeric sleeve; a self-expandable wire structure at least partially encapsulated by the sleeve at a proximal end of the sleeve, wherein, in its expanded form, the wire structure is adapted to exert an outward pressure against a portion of a wall of an intestine to position the entire intestinal barrier, including the self-expandable wire structure, within the intestine distal to a pylorus; and at least one barb or hook configured to engage with the intestine, wherein a diameter of the self-expandable wire structure at the proximal end of the sleeve is greater than a diameter of a distal-most end of the sleeve.