发明名称 USE OF ALPHA-KETOGLUTARATE IN THE TREATMENT OF HYPERTENSION
摘要 The invention relates to the use of at least one member selected from the group consisting of: a. alpha-ketoglutaric acid (AKG); b. pharmaceutically acceptable salts of alpha-ketoglutaric acid; c. amides of an amino-acid, a dipeptide or a tripeptide and alpha-ketoglutaric acid and pharmaceutically acceptable salts thereof; and d. pharmaceutically acceptable physical mixtures of alpha-ketoglutaric acid or a pharmaceutically acceptable salt thereof and at least one amino acid or a pharmaceutically acceptable salt thereof for the manufacture of a pharmaceutical preparation or a food or feed supplement for the treatment of hypertension or pulmonary hypertension improving blood vessel elasticity in a subject in need thereof.
申请公布号 CA2691746(C) 申请公布日期 2016.02.02
申请号 CA20082691746 申请日期 2008.06.27
申请人 ENTRESS AB 发明人 PIERZYNOWSKI, STEFAN G.
分类号 A61K31/194;A61K31/198;A61P9/14 主分类号 A61K31/194
代理机构 代理人
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