发明名称 |
TREATMENT OF INFLAMMATORY CONDITIONS BY MODULATION OF HYALURONAN AND HYALURONIDASE ACTIVITY |
摘要 |
The present invention describes compositions and related methods and kits for treating a variety of inflammatory conditions and infections. The therapeutic compositions include certain hyaluronidases capable of generating hyaluronan disaccharides when combined with hyaluronan, and/or the hyaluronan disaccharides themselves, and/or inflammatory hyaluronidase inhibitors. The invention further discloses the use of hyaluronidase inhibitors to treat certain infections in an individual. |
申请公布号 |
US2016022715(A1) |
申请公布日期 |
2016.01.28 |
申请号 |
US201414782269 |
申请日期 |
2014.04.03 |
申请人 |
CEDARS-SINAI MEDICAL CENTER |
发明人 |
Liu George;Kyme Pierre |
分类号 |
A61K31/7016;C12N9/26;A61K38/47 |
主分类号 |
A61K31/7016 |
代理机构 |
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代理人 |
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主权项 |
1. A method for treating and/or inhibiting an inflammatory condition in a subject, comprising administering a therapeutically effective amount of a composition comprising hyaluronan disaccharide to the subject. |
地址 |
Los Angeles CA US |