发明名称 TREATMENT OF INFLAMMATORY CONDITIONS BY MODULATION OF HYALURONAN AND HYALURONIDASE ACTIVITY
摘要 The present invention describes compositions and related methods and kits for treating a variety of inflammatory conditions and infections. The therapeutic compositions include certain hyaluronidases capable of generating hyaluronan disaccharides when combined with hyaluronan, and/or the hyaluronan disaccharides themselves, and/or inflammatory hyaluronidase inhibitors. The invention further discloses the use of hyaluronidase inhibitors to treat certain infections in an individual.
申请公布号 US2016022715(A1) 申请公布日期 2016.01.28
申请号 US201414782269 申请日期 2014.04.03
申请人 CEDARS-SINAI MEDICAL CENTER 发明人 Liu George;Kyme Pierre
分类号 A61K31/7016;C12N9/26;A61K38/47 主分类号 A61K31/7016
代理机构 代理人
主权项 1. A method for treating and/or inhibiting an inflammatory condition in a subject, comprising administering a therapeutically effective amount of a composition comprising hyaluronan disaccharide to the subject.
地址 Los Angeles CA US