发明名称 |
PREPARATION OF A SOLID FORM OF GADOBENATE DIMEGLUMINE |
摘要 |
The present invention relates to a process for the preparation of a solid form of the gadobenate dimeglumine compound that comprises obtaining a solution of the said compound in a suitable solvent A wherein the amount by weight of the water optionally present in the solution is at most equal to or lower than the amount by weight of the gadobenate dimeglumine comprised in the solution and adding the obtained solution to an organic solvent B, acting as an appropriate antisolvent and favoring the formation of a solid form of the gadobenate dimeglumine that can be collected by filtration. |
申请公布号 |
WO2016012386(A1) |
申请公布日期 |
2016.01.28 |
申请号 |
WO2015EP66512 |
申请日期 |
2015.07.20 |
申请人 |
BRACCO IMAGING SPA |
发明人 |
MAZZON, ROBERTA;FRETTA, ROBERTA;ANELLI, PIER LUCIO |
分类号 |
C07C227/38;A61K9/00 |
主分类号 |
C07C227/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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