发明名称 |
Multivalent immunoglobulins modified in the structural loop region |
摘要 |
The present invention provides a multivalent immunoglobulin or part thereof binding specifically to at least two cell surface molecules of a single cell with at least one modification in at least one structural loop region of said immunoglobulin determining binding to an epitope of said cell surface molecules wherein the unmodified immunoglobulin does not significantly bind to said epitope, its use and methods for producing it. |
申请公布号 |
HUE025035(T2) |
申请公布日期 |
2016.01.28 |
申请号 |
HUE11194316 |
申请日期 |
2007.06.26 |
申请人 |
F-Star Biotechnologische Forschungs- und Entwicklungsges.m.b.H |
发明人 |
Rueker, Florian;Himmler, Gottfried;Wozniak-Knopp, Gordana |
分类号 |
C07K16/00;C07K16/28;C07K16/46;C07K19/00;C12N15/62 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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