发明名称 |
SEQUESTRANTS OF ADVANCED GLYCATION END PRODUCT (AGE) PRECURSORS |
摘要 |
Sequestrants of AGE precursors comprise amines separated by 2, 3 or 4 carbons. Sequestrants of AGE precursors can be used as pharmaceutical agents and in pharmaceutical compositions. The sequestrants of AGE precursors are particularly useful binding AGE precursors and dietary dicarbonyls in mammals in the gastrointestinal tract for the treatment of ailments such as diabetic nephropathy, chronic renal disease, atherosclerosis, stroke, cataracts, and Alzheimer's disease. |
申请公布号 |
EP2968403(A1) |
申请公布日期 |
2016.01.20 |
申请号 |
EP20140715503 |
申请日期 |
2014.03.12 |
申请人 |
GENZYME CORPORATION |
发明人 |
HOLMES-FARLEY, STEPHEN, RANDALL;DHAL, PRADEEP;BESEV, MAGNUS;MILLER, ROBERT, J.;PAPOULIS, ANDREW, T. |
分类号 |
A61K31/785;A61P9/10;A61P13/12;A61P25/28;A61P27/12 |
主分类号 |
A61K31/785 |
代理机构 |
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代理人 |
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地址 |
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