主权项 |
1. A polynucleotide (referred as “αCDR3 polynucleotide”) having a nucleotide sequence selected from the group consisting of SEQ ID NOs: 1, 3, 5, 8, 10, 11, 13, 14, 16, 18, 20, 22, 23, 25, 27, 28, 30, 31, 33, 35, 37, 39, 41, 43, 45, 47, 49, 51, 53, 55, 56 and 58, wherein said polynucleotide encodes CDR3 of α-chain of TCR of a CD4+ helper T-cell specific to a WT1 helper peptide (WT1332 peptide) having an amino acid sequence shown in SEQ ID NO: 123 or a variant sequence thereof. |