| 发明名称 | Pharmacological treatment of Parkinson's disease | ||
| 摘要 | The present invention relates to the co-administration of two neurotransmitter agonists to patients with motor disorders, for the purpose of symptom reduction. In particular the present invention provides methods and compositions for alleviation of akinesia, rigidity and/or tremor associated with Parkinson's disease. | ||
| 申请公布号 | US9226904(B2) | 申请公布日期 | 2016.01.05 |
| 申请号 | US201012730972 | 申请日期 | 2010.03.24 |
| 申请人 | The United States of America as Represented by the Department of Veterans Affairs | 发明人 | Wolf William A.;Istre Erik D. |
| 分类号 | A61K31/198;A61K31/496;A61K31/137;A61K31/55;A61K31/497;A61K45/06 | 主分类号 | A61K31/198 |
| 代理机构 | Klauber & Jackson LLC | 代理人 | Klauber & Jackson LLC |
| 主权项 | 1. A method of reducing dyskinesia elicited by L-DOPA in a subject having Parkinson's disease treated with L-DOPA, said method comprising administering an amount of L-DOPA to said subject sufficient to provide an anti-Parkinsonian effect in said subject and wherein said method further comprises administering to said subject an amount of eltoprazine sufficient to reduce dyskinesia elicited by said L-DOPA. | ||
| 地址 | Washington DC US | ||