Compositions and methods for measurement of oxygen saturation in blood filled structures

摘要

Provided herein is technology relating to medical monitoring of physiologic parameters, and particularly, but not exclusively, relating to compositions, methods and systems for the measurement of venous and arterial oxygen saturation in the blood of blood-filled anatomical structures.

主权项

1. A method for measuring blood oxygen saturation in a blood-filled structure comprising:
a) providing a system comprising:
1) at least one oximeter sensor comprising;
i) at least two light sources of differing wavelength;ii) at least one photodetector; andiii) a sensor housing comprising:
a′) a flexible tubular member;b′) an optically transparent electrically isolated sheath; andc′) a cable comprising at least one connector;2) a processor comprising:
i) a controller adapted for analyzing a plurality of signals from said oximeter sensor, calculating oxygen saturation values from the signals, and generating a distribution of the relative frequency of occurrence of oxygen saturations obtained within defined intervals of oxygen saturation at a plurality of predetermined averaging intervals; and3) a display configured to output the distribution calculated by the processor; b) positioning said oximeter sensor in a position adjacent to a blood-filled structure of a subject while displaying said distribution and using said displayed information to optimize said positioning relative to said blood-filled structure; and c) measuring said blood oxygen saturation in said blood filled structure of said subject with said oximeter sensor at the optimized position.