发明名称 |
Oral treatment of inflammatory bowel disease |
摘要 |
Treatment of an inflammatory bowel disease in a subject in need thereof by simultaneous or successive parenteral and oral administration of a mammalian beta defensin is described. Oral administration of mammalian beta defensin to a subject during remission to keep said subject suffering from IBD in remission, prolong remission in said subject suffering from IBD, to reduce the occurrence of relapse in said subject suffering from IBD, or any combination thereof, is also described. |
申请公布号 |
US9217021(B2) |
申请公布日期 |
2015.12.22 |
申请号 |
US201214131364 |
申请日期 |
2012.07.05 |
申请人 |
Defensin Therapeutics ApS |
发明人 |
Rosenkilde Kjær Tanja Maria;Andersen Birgitte;Brinch Karoline Sidelmann |
分类号 |
A61K31/04;A61K38/17;A61K38/00;C07K14/47 |
主分类号 |
A61K31/04 |
代理机构 |
Hamilton, Brook, Smith & Reynolds, P.C. |
代理人 |
Hamilton, Brook, Smith & Reynolds, P.C. |
主权项 |
1. A method of treating an inflammatory bowel disease (IBD) in a subject diagnosed with IBD but in remission, said method comprising; orally administering a mammalian beta defensin to said subject in an effective amount: a) to keep said subject in remission, b) to prolong remission in said subject, or c) to reduce the occurrence of relapse in said subject, or any combination thereof. |
地址 |
Gentofte DK |