| 发明名称 |
Process for the preparation of biphosphonic acids and salts thereof |
| 摘要 |
A process for the preparation of biphosphonic acids and pharmaceutical acceptable salts thereof, comprises reacting a carboxylic acid with phosphorous trichloride and phosphorous acid in the presence of an aprotic polar solvent. Formula (I): |
| 申请公布号 |
ZA200903228(B) |
申请公布日期 |
2010.01.27 |
| 申请号 |
ZA20090003228 |
申请日期 |
2009.05.11 |
| 申请人 |
HOVIONE INTER LIMITED |
发明人 |
BAPTISTA, JOANA;MENDES, ZITA |
| 分类号 |
C07F |
主分类号 |
C07F |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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