Liquid granulocyte colony-stimulating factor formulation, e.g. for treating cancer, neutropenia, HIV infections or neurological disorders, comprises a sugar alcohol, surfactant and acetate buffer

摘要

Aqueous liquid formulation of granulocyte colony-stimulating factor (G-CSF) comprises G-CSF, a sugar alcohol, a surfactant (0.04-0.06 mg/ml), an acetate buffer (5-20 mM, pH 4.1-4.4) and optionally amino acids, glyccerol, carbohydrates and/or preservatives. An independent claim is also included for a vessel containing a formulation as above. ACTIVITY : Cytostatic; Immunostimulant; Anti-HIV; Neuroprotective. MECHANISM OF ACTION : Granulocyte colony-stimulating factor.