MULTI-VESICULAR LIPOSOME, THE METHOD PREPARING THEREOF AND THE PHARMACEUTICAL OR COSMETIC COMPOSITION CONTAINING THE SAME

摘要

PURPOSE: A method for preparing a multi-vesicular liposome is provided to quickly release drugs to a specific site and to enable easy and efficient absorption. CONSTITUTION: A method for preparing a multi-vesicular liposome comprises: a step of dissolving one or more biologically active materials and measuring mole osmosis concentration to obtain a first aqueous phase; a step of dissolving a lipid mixture of an acid amphiphilic material in an organic solvent; a step of capsulating the biologically active material to form a water-in-oil emulsion; a step of mixing the water-in-oil emulsion in a second aqueous phase to obtain a W/O/W emulsion or a disperse water-in-oil emulsion in a second aqueous phase; and a step of removing an organic solvent to form a multi-vascular liposome.