发明名称 METHODS OF CONVERSION OF INTERFERON ISOFORMS AND PRODUCTS THEREOF
摘要 The present invention provides methods for isolating adjunct isoforms of proteins and converting them to the desired protein. In preferred embodiments, the present invention contemplates the use of acid solutions or zinc solutions to cleave a chemical group from a desired protein. In further preferred embodiments, the present invention contemplates the oxidation of reduced sulfhydryl groups with cleavage of chemical groups to form a functional desired protein.
申请公布号 CA2348739(C) 申请公布日期 2010.05.11
申请号 CA19992348739 申请日期 1999.10.05
申请人 SCHERING CORPORATION 发明人 CANNON-CARLSON, SUSAN;FREI, ANDRES;LEE, SEOJU;MENGISEN, ROLAND;VOLOCH, MARCIO;WYLIE, DAVID C.
分类号 C07K14/52;C07K14/56;A61K38/00;C07K1/02;C07K1/16 主分类号 C07K14/52
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