| 发明名称 |
MONOCLONAL ANTIBODIES, CROSS-REACTIVE ANTIBODIES AND METHOD FOR PRODUCING THE SAME |
| 摘要 |
<p>A method of making monoclonal antibodies according to a mixed antigen immunization protocol is described. In addition, antibodies obtainable by the method are disclosed which specifically cross-react with two or more different receptors to which Apo-2 ligand (Apo-2L) can bind.</p> |
| 申请公布号 |
EP1086138(B1) |
申请公布日期 |
2009.09.23 |
| 申请号 |
EP19990928574 |
申请日期 |
1999.06.10 |
| 申请人 |
GENENTECH, INC. |
发明人 |
ASHKENAZI, AVI, J.;CHUNTHARAPAI, ANAN;KIM, K., JIN |
| 分类号 |
C07K16/28;G01N33/531;A61K38/00;A61K39/00;A61K39/395;A61P35/00;C07K14/705;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/02;C12N15/85;C12P21/08;C12R1/91 |
主分类号 |
C07K16/28 |
| 代理机构 |
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