The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables Q and R are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.
申请公布号
CA2713718(A1)
申请公布日期
2009.09.03
申请号
CA20092713718
申请日期
2009.02.16
申请人
F. HOFFMANN-LA ROCHE AG
发明人
DU BOIS, DAISY JOE;ELWORTHY, TODD RICHARD;HENDRICKS, ROBERT THAN;HERMANN, JOHANNES CORNELIUS;KONDRU, RAMA K.;LOU, YAN;OWENS, TIMOTHY D.;PARK, JAEHYEON;SMITH, DAVID BERNARD;SOTH, MICHAEL