发明名称 DIHYDROPYRROLONAPHTYRIDINONE COMPOUNDS AS INHIBITORS OF JAK
摘要 Disclosed are JAK inhibitors of formula I where G1, R1, R2, R3, R4, R5, R6, and R7 are defined in the specification. Also disclosed are pharmaceutical compositions, kits and articles of manufacture which contain the compounds, methods and materials for making the compounds, and methods of using the compounds to treat diseases, disorders, and conditions involving the immune system and inflammation, including rheumatoid arthritis, hematological malignancies, epithelial cancers (i.e., carcinomas), and other diseases, disorders or conditions associated with JAK.
申请公布号 US2011136780(A1) 申请公布日期 2011.06.09
申请号 US20100796583 申请日期 2010.06.08
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 DONG QING;KANOUNI TOUFIKE;LAWSON JOHN DAVID;WALLACE MICHAEL B.
分类号 A61K31/4375;A61K31/496;A61K31/506;A61K31/519;A61K31/5377;A61K31/541;A61P11/00;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P25/00;A61P37/08;C07D471/16 主分类号 A61K31/4375
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