发明名称 |
CLOSTRIDIAL NEUROTOXINS WITH ALTERED PERSISTENCY |
摘要 |
The invention relates to a polypeptide comprising: (a) a HC-domain or fragment thereof of the neurotoxic component of a clostridial toxin; and (b) a first LC domain or fragment thereof of the neurotoxic component of a clostridial toxin; and (c) at least one further LC domain or fragment thereof of the neurotoxic component of a clostridial toxin wherein the first and the at least one further LC domain may be the same or different from each other, and wherein each of said fragments of said first and of said at least one further LC domain still exhibits proteolytic activity. |
申请公布号 |
KR20110060903(A) |
申请公布日期 |
2011.06.08 |
申请号 |
KR20117006528 |
申请日期 |
2009.08.28 |
申请人 |
MERZ PHARMA GMBH & CO. KGAA |
发明人 |
FREVERT JUERGEN |
分类号 |
C07K14/33;A61K39/08;C07K16/12;C12N15/31 |
主分类号 |
C07K14/33 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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