The present invention relates to polymeric derivatives, which can be conjugated to an amino-containing drug to improve its in vivo properties. The polymeric derivative can subsequently be released to yield the drug in its native form. Methods of preparing and using these polymeric derivatives and drug conjugates are described.
申请公布号
EP2328619(A2)
申请公布日期
2011.06.08
申请号
EP20090791780
申请日期
2009.08.21
申请人
BAXTER INTERNATIONAL INC.;BAXTER HEALTHCARE SA
发明人
YANG, GUOHAN;HAI, TON, THAT;MELNICK, BENNETT;SANDERS, PAUL;JIANG, CONG;QUINN, CATHERINE;LI, JIE;AMBROISE, AROUNAGUIRY;BROWN, LARRY, R.