| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a monoclonal antibody obtained from organisms with autoimmune disease, which recognizes viral antigens and neutralizes virus infectious capability, and particularly, a monoclonal antibody that recognizes antigenic polypeptide products and homologs thereof encoded by human endogenous retroviral sequences (HERVs). <P>SOLUTION: There are provided monoclonal antibodies and antibody fragments which recognize antigens encoded by HERV (human endogenous retroviral sequence) DNA sequences, and methods for production, including recombinant antibody fragments derived from lymphoid cells of lupus patients that make antibodies which neutralize HIV. <P>COPYRIGHT: (C)2011,JPO&INPIT</p> |
