| 摘要 |
PROBLEM TO BE SOLVED: To provide a new compound having an action as a strong mGluR2 positive modulator and being useful as a therapeutic agent of mental illness and neurodegenerative disease in which a mGluR2 of schizophrenia, anxiety disorder, or the like is involved.SOLUTION: A compound of formula (I) or a pharmaceutically acceptable salt thereof is provided [wherein Rrepresents a 1-10C alkyl or the like, X represents a hydrogen atom, a halogen or the like, Y represents a 1-6C alkyl or the like, n represents an integer of 0 to 4, Z represents -L-A-L-Bor the like, Lrepresents a single bond or the like, A represents an arylene or the like, Lrepresents a single bond or the like, and Brepresents an aryl or the like]. |
