发明名称 |
HSV-1 EPITOPES AND METHODS FOR USING SAME |
摘要 |
The invention provides HSV antigens and epitopes that are useful for the prevention and treatment of HSV infection. T-cells having specificity for antigens of the invention have demonstrated cytotoxic activity against cells loaded with virally-encoded peptide epitopes, and in many cases, against cells infected with HSV. The identification of immunogenic antigens responsible for T-cell specificity provides improved anti-viral therapeutic and prophylactic strategies. Compositions containing antigens or polynucleotides encoding antigens of the invention provide effectively targeted vaccines for prevention and treatment of HSV infection.
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申请公布号 |
US2013224236(A1) |
申请公布日期 |
2013.08.29 |
申请号 |
US201113882405 |
申请日期 |
2011.11.03 |
申请人 |
KOELLE DAVID M.;JING LICHEN;UNIVERSITY OF WASHINGTON |
发明人 |
KOELLE DAVID M.;JING LICHEN |
分类号 |
C07K14/035 |
主分类号 |
C07K14/035 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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