PHARMACEUTICAL FORMULATIONS CONTAINING MICROEMULSION OF ANTIFUNGAL AGENTS

摘要

The present invention provides pharmaceutical formulations containing oil in water microemulsion of antifungal agents, preferably terconazole. These formulations are of two types, one which are viscous liquids capable of forming thermoreversible gel at body temperature and two which are gels at room temperature. Thermoreversible gel produced according to present invention shows sustained/controlled release up to 12 hrs. The invention also provides process of preparation of these pharmaceutical formulations. These pharmaceutical formulations possess excellent bioadhesive potential compared to marketed products.