发明名称 Use of testosterone and a 5-HT1A agonist in the treatment of sexual dysfunction
摘要 The invention relates to the field of male and/or female sexual dysfunction. The invention specifically relates to the use of testosterone and a 5-HT1A agonist.
申请公布号 US9211334(B2) 申请公布日期 2015.12.15
申请号 US201314049005 申请日期 2013.10.08
申请人 EB IP LYBRIDOS B.V. 发明人 Tuiten Jan Johan Adriaan;Bloemers Johannes Martinus Maria;De Lange Robertus Petrus Johannes
分类号 A61K31/56;A61K45/06;A61K31/496;A61K31/519;A61K31/568 主分类号 A61K31/56
代理机构 Morrison & Foerster LLP 代理人 Morrison & Foerster LLP
主权项 1. A pharmaceutical composition designed for acute administration in anticipation of sexual activity comprising testosterone and a 5-HT1A agonist, wherein said testosterone is formulated for sublingual, buccal-mucosal, or intranasal administration with a cyclodextrin to release the testosterone within 120 seconds after administration with peak levels of testosterone reached after about 1-20 minutes and the 5-HT1A agonist is formulated for delayed release such that 5-HT1A is released 2.5 to 4.5 hours after the release of testosterone.
地址 Almere NL