发明名称 |
Use of testosterone and a 5-HT1A agonist in the treatment of sexual dysfunction |
摘要 |
The invention relates to the field of male and/or female sexual dysfunction. The invention specifically relates to the use of testosterone and a 5-HT1A agonist. |
申请公布号 |
US9211334(B2) |
申请公布日期 |
2015.12.15 |
申请号 |
US201314049005 |
申请日期 |
2013.10.08 |
申请人 |
EB IP LYBRIDOS B.V. |
发明人 |
Tuiten Jan Johan Adriaan;Bloemers Johannes Martinus Maria;De Lange Robertus Petrus Johannes |
分类号 |
A61K31/56;A61K45/06;A61K31/496;A61K31/519;A61K31/568 |
主分类号 |
A61K31/56 |
代理机构 |
Morrison & Foerster LLP |
代理人 |
Morrison & Foerster LLP |
主权项 |
1. A pharmaceutical composition designed for acute administration in anticipation of sexual activity comprising testosterone and a 5-HT1A agonist, wherein said testosterone is formulated for sublingual, buccal-mucosal, or intranasal administration with a cyclodextrin to release the testosterone within 120 seconds after administration with peak levels of testosterone reached after about 1-20 minutes and the 5-HT1A agonist is formulated for delayed release such that 5-HT1A is released 2.5 to 4.5 hours after the release of testosterone. |
地址 |
Almere NL |