发明名称 |
VARIANT ACTIVIN RECEPTOR POLYPEPTIDES, ALONE OR IN COMBINATION WITH CHEMOTHERAPY, AND USES THEREOF |
摘要 |
The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides and proteins. Compositions and methods for treating muscle-wasting and other diseases and disorders are also provided. |
申请公布号 |
HK1203384(A1) |
申请公布日期 |
2015.12.11 |
申请号 |
HK20150103990 |
申请日期 |
2015.04.24 |
申请人 |
AMGEN INC. |
发明人 |
SUN, JEONGHOON;TAM, LEI-TING TONY;HAN, HUIQUAN;KWAK, KEITH SOO-NYUNG;ZHOU, XIAOLAN;LU, JOHN |
分类号 |
A61K;A61P;C07K |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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