发明名称 |
GROWTH FACTOR SEQUESTERING AND PRESENTING HYDROGELS |
摘要 |
Provided herein are hydrogel cell matrices, hydrogel cell matrix systems for the support, growth, and differentiation of a stem cell or progenitor cell and methods for making such hydrogel cell matrices. |
申请公布号 |
US2015352156(A1) |
申请公布日期 |
2015.12.10 |
申请号 |
US201414760141 |
申请日期 |
2014.01.16 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
Jha Amit Kumar;Healy Kevin E. |
分类号 |
A61K35/44;C07K14/495;A61K47/48;A61K38/18;A61K9/00 |
主分类号 |
A61K35/44 |
代理机构 |
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代理人 |
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主权项 |
1. A hydrogel cell matrix comprising:
a) a plurality of hydrogel polymers; b) a cell adhesion peptide conjugated to one or more hydrogel polymers; c) a factor release molecule conjugated to one or more hydrogel polymers; and d) a proteolytically cleavable cross-linker peptide that links one or more hydrogel polymers of the plurality of hydrogel polymers to another hydrogel polymer of the plurality. |
地址 |
Oakland CA US |