Tetrazolo hydrazine derivatives and pharmaceutical composition comprising same as active ingredient for preventing or treating cancer

摘要

Provided are novel tetrazolo hydrazone derivatives or pharmaceutically acceptable salts thereof. The derivatives and the salts may inhibit the proliferation of cancer cells in a low molar concentration and inhibit the activity of cancer cells through the regulation of expression of apoptosis-related genes or the like, thus expressing excellent anti-cancer activity, and therefore, can be used effectively in preventing or treating cancer.

主权项

1. Tetrazolo hydrazone derivatives represented by the following Formula 1 or pharmaceutically acceptable salts thereof: wherein, R1, R2, R3, R4 and R5 are independently H, halogen, NO2, C1-4 alkyl, C1-4 haloalkyl or C1-4 alkoxy.