Bridged bicyclic heteroaryl substituted triazoles useful as Axl inhibitors

摘要

Bridged bicyclic heteroaryl substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein tyrosine kinase Axl. Methods of using the compounds in treating diseases or conditions associated with Axl activity are also disclosed.

主权项

1. A compound of formula (VI): wherein: R10 is selected from the group consisting of halo, pyridinyl and phenyl, where the phenyl is optionally substituted by one or more substituents selected from the group consisting of halo, cyano, alkoxy and alkyl; as an isolated stereoisomer or a mixture thereof, or as a pharmaceutically acceptable salt thereof.