ANTIBODY AGAINST THE PROTEIN TRIO AND ITS METHOD OF PRODUCTION

摘要

Disclosed are specific antibodies against the protein Trio, their method of production, and their use in in vitro cancer prognostic method. Also described are the antigens enabling production of the antibodies.

主权项

1. An antigen constituted of from 50 to 400 amino acids, said antigen comprising a polypeptide P1,
which is a peptide of at least 50 contiguous amino acids belonging to the polypeptide represented by sequence SEQ ID NO: 1;with the proviso thatLSGGCELTVVIHDFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTTDRSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHK is excluded,or
which is a peptide having at least 90%, in particular 95%, especially 98% of sequence homology with the amino acid sequence of SEQ ID NO: 1,in particular the polypeptide P1 being represented by amino acid sequence SEQ ID NO: 1,with the proviso thatLSGGCELTVVIHDFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTTDRSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHK is excluded.