METHOD FOR DIAGNOSING CANCERS EXPRESSING HER2 RECEPTOR OR ITS TRUNCATED VARIANTS

摘要

PROBLEM TO BE SOLVED: To provide a method of diagnosis and therapy of cancers expressing the HER2 receptor.SOLUTION: The invention provides antibodies or fragments thereof that recognizes an epitope of a HER2 receptor truncated form, the epitope being defined by a specific sequence. The invention also provides a method of cancer diagnosis, which comprises the detection of the presence of the HER2 receptor truncated form consisting of a specific amino acid sequence in a patient sample.