发明名称 |
Use of Inhibitors of the Activity or Function of PI3K |
摘要 |
The invention relates to new uses of PI3K inhibitors, wherein said inhibitors have an inhibitory action on the PI3K isoform delta for the treatment of immunopathology in a subject suffering from a disease or disorder selected from malaria, leishmaniasis, trypanosomiasis, toxoplasmosis and/or neurocysticercosis, via functional inhibition of TLR9 of the infected subject. |
申请公布号 |
US2015342951(A1) |
申请公布日期 |
2015.12.03 |
申请号 |
US201214365512 |
申请日期 |
2012.12.14 |
申请人 |
NOVARTIS AG |
发明人 |
COOKE Nigel Graham;FERNANDES GOMES DOS SANTOS Paulo Antonio;FURET Pascal;HEBACH Christina;HOGENAUER Klemens;HOLLINGWORTH Gregory;KALIS Christoph;LEWIS Ian;SMITH Alexander Baxter;SOLDERMANN Nicolas;STAUFFER Frederic;STRANG Ross;STOWASSER Frank;TUFFILLI Nicola;VON MATT Anette;WOLF Romain;ZECRI Frederic |
分类号 |
A61K31/519;A61K31/551;A61K31/541;A61K31/5377;A61K31/517 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Basel CH |