发明名称 |
SUBCUTANEOUS ADMINISTRATION OF IDURONATE- 2-SULFATASE |
摘要 |
The present invention provides, among other things, compositions, kits and methods for subcutaneous delivery of lysosomal enzymes for effective treatment of lysosomal storage diseases. In some embodiments, the present invention provides methods for treating Hunter syndrome by subcutaneous administration of a replacement iduronate-2-sulfatase (I2S) protein. In some embodiments, the present invention provides a kit comprising an arrangement of components for subcutaneously administering iduronate-2-sulfatase (I2S) protein. |
申请公布号 |
EP2830642(A4) |
申请公布日期 |
2015.12.02 |
申请号 |
EP20130769624 |
申请日期 |
2013.03.14 |
申请人 |
SHIRE HUMAN GENETIC THERAPIES, INC. |
发明人 |
XIE, HONGSHENG;FELICE, BRIAN;MCCAULEY, THOMAS |
分类号 |
A61K38/00;A61K38/43;A61P25/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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