A METHOD AND SYSTEM FOR ASSESSING FIBROSIS IN A TISSUE

摘要

A method for assessing fibrosis in a tissue is proposed. The method uses a test image which is an image of the tissue and comprises identifying, from the test image, a portal collagen area, a septal collagen area and a fibrillar collagen area respectively comprising pixels representing portal collagen, septal collagen and fibrillar collagen of the tissue, obtaining quantitative values of one or more features for each identified area based on characteristics of the identified area in the test image and assessing fibrosis using the quantitative values obtained for all the identified areas.

主权项

1. A method for assessing fibrosis in a tissue using a test image which is an image of the tissue, wherein the test image comprises a plurality of pixels having respective intensity values and wherein the method comprises:
(1a) automatically identifying, from the test image, a portal collagen area, a septal collagen area and a fibrillar collagen area respectively comprising pixels representing portal collagen, septal collagen and fibrillar collagen of the tissue, the fibrillar collage including collagen in both peri-cellular and peri-sinusoidal spaces; (1b) obtaining quantitative values of one or more features for each identified area based on characteristics of the identified area in the test image; and (1c) assessing fibrosis using the quantitative values obtained for all the identified areas.