| 摘要 |
The present invention relates to a composition for preventing and treating hepatic diseases, comprising sulforaphane (SFN) as an active ingredient. It is confirmed that the sulforaphane (SFN): showed lower accumulation of fat, decreased the levels of TG, FFA, and TC in plasma and the activities of ALT and AST in plasma, and greatly reduced total visceral fat-pad, body weight (50%), weight gain (-47%), and food efficiency ratio (-34%), in experiments in preventive effects on HFD-induced hepatic steatosis specimens (experimental example 1); and significantly increased the level of circulating adiponectin and mRNA expression of adiponectin, and stimulated expression of adipoR2 in liver tissue in experiments in effects on the expression of steatosis-related genes (experimental example 2), thereby being able to be effectively used as a composition and a health functional food for preventing and treating hepatic diseases. |
