发明名称 |
PHTHALAZINONES AND ISOQUINOLINONES AS ROCK INHIBITORS |
摘要 |
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same. |
申请公布号 |
EP2945943(A2) |
申请公布日期 |
2015.11.25 |
申请号 |
EP20140702408 |
申请日期 |
2014.01.17 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
GLUNZ, PETER W.;ZOU, YAN;QUAN, MIMI L.;LADZIATA, VLADIMIR |
分类号 |
C07D403/12;C07D237/32;C07D401/10;C07D401/12;C07D403/10;C07D405/12;C07D413/10;C07D413/12;C07D417/10;C07D417/12;C07D417/14;C07D471/04;C07D487/04;C07D491/048;C07D513/04 |
主分类号 |
C07D403/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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