发明名称 Adjuvant
摘要 The invention relates to a new adjuvant and to its use in combination with an antigen.
申请公布号 US9187751(B2) 申请公布日期 2015.11.17
申请号 US201113884939 申请日期 2011.11.10
申请人 LABORATORIOS LETI, S.L. 发明人 Alonso-Bedate Carlos;Soto-Alvarez Manuel;Parody-De La Fuente Nuria;Pico De Coana-Suarez Yago
分类号 C12N15/67;C07K14/44;C07H21/02;A61K39/00 主分类号 C12N15/67
代理机构 Morgan, Lewis & Bockius LLP 代理人 Morgan, Lewis & Bockius LLP
主权项 1. A nucleic acid molecule having a nucleotide sequence selected from the group consisting of: i. nucleotide sequences encoding a polypeptide comprising an amino acid sequence that has at least 50% sequence identity with the amino acid sequence of SEQ ID NO:1 over its entire length, ii. nucleotide sequences comprising a nucleotide sequence that has at least 50% sequence identity with the nucleotide sequence of SEQ ID NO:2 over its entire length, iii. nucleotide sequences the complementary strand of which hybridizes to a nucleic acid molecule of sequence of (i) or (ii) and iv. nucleotide sequences which differ from the nucleotide sequence of (iii) due to the degeneracy of the genetic code, wherein said nucleotide sequence is operably linked to a nucleotide sequence encoding an antigen, and wherein said nucleic acid molecule is free of a sequence encoding for a polypeptide identical to SEQ ID NO: 3 over its entire length.
地址 Madrid ES