PROTEIN REMOVAL AGENT

摘要

The present invention provides compositions, methods and kits for the removal of proteins from complex reaction mixtures useful in majority workflows of molecular biology research experiments. More specifically, such compositions, methods and kits are useful in such processes as purification of nucleic acids from biological samples or after their treatment with specific enzymes, when residual enzyme activity in reaction mixture is not compatible with downstream applications.

主权项

1. A composition for removing protein contaminants from a solution containing a target nucleic acid, the composition comprising
(i) a polyacid comprising a polycarboxylic acid, a polyphosphonic acid, or a polycarboxylate or polyphosphonate salt; and (ii) a solid phase comprising a functionalized silica surface.