发明名称 Antagonistas ciclohexil-azetidinilo de CCR2
摘要 <p>The present invention comprises compounds of Formula I. wherein: R1, R2, R4, J, Q, and A are as defined in the specification. The invention also comprises a method of preventing, treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is type II diabetes, obesity and asthma. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.</p>
申请公布号 ES2550312(T3) 申请公布日期 2015.11.06
申请号 ES20110729234T 申请日期 2011.06.16
申请人 JANSSEN PHARMACEUTICA NV 发明人 LANTER, JAMES C.;MARKOTAN, THOMAS P.;SUBASINGHE, NALIN;SUI, ZHIHUA
分类号 C07D401/12;A61K31/4375;A61K31/4709;A61K31/502;A61K31/517;A61P29/00;C07D401/14;C07D403/12;C07D403/14;C07D405/14;C07D413/14;C07D417/14;C07D471/04 主分类号 C07D401/12
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