发明名称 |
métodos para diagnosticar proliferação peroxissomal aumentada e para identificar uma substância para tratar proliferação peroxissomal aumentada, e, uso de pelo menos cinco analitos e de meios para a determinação de pelo menos cinco analitos |
摘要 |
The present invention pertains to the field of toxicological assessments for risk stratification of chemical compounds. Specifically, it relates to a method for diagnosing increased peroxisomal proliferation. It also relates to a method of determining whether a compound is capable of inducing such peroxisomal proliferation in a subject and to a method of identifying a drug for treating increased peroxisomal proliferation. Furthermore, the present invention relates to a data collection including characteristic values of at least five metabolites, a data storage medium including data collection, and a system and a device for diagnosing increased peroxisomal proliferation. Finally, the present invention pertains to the use of a group of metabolites or means for the determination thereof for the manufacture of a diagnostic device or composition for diagnosing increased peroxisomal proliferation in a subject. |
申请公布号 |
BRPI0912136(A2) |
申请公布日期 |
2015.11.03 |
申请号 |
BR2009PI12136 |
申请日期 |
2009.05.26 |
申请人 |
BASF SE |
发明人 |
ALEXANDRE PROKOUDINE;BENNARD VAN RAVENZWAAY;EDGAR LEIBOLD;ERIC FABIAN;GEORGIA COELHO PALERMO CUNHA;HENNICKE KAMP;JAN C. WIEMER;MICHAEL MANFRED HEROLD;RALF LOOSER;TILMANN B. WALK;VOLKER STRAUSS;WERNER MELLERT |
分类号 |
G01N33/68;G01N33/82;G01N33/84;G01N33/92 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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