发明名称 |
Crystalline form of pemetrexed disodium |
摘要 |
The present invention relates to a new polymorphic or crystalline form of Pemetrexed Disodium, processes for its preparation and its use, in particular for the preparation of medicaments. |
申请公布号 |
US9174991(B2) |
申请公布日期 |
2015.11.03 |
申请号 |
US201013511723 |
申请日期 |
2010.11.24 |
申请人 |
Azad Pharmaceutical Ingredients AG;University of Zurich |
发明人 |
Albrecht Uwe Jens;Helmboldt Hannes;Nikolaev Vsevolod Valerievich |
分类号 |
C07D487/04;A61K31/519;A61P35/00 |
主分类号 |
C07D487/04 |
代理机构 |
Rothwell, Figg, Ernst & Manbeck, P.C. |
代理人 |
Rothwell, Figg, Ernst & Manbeck, P.C. |
主权项 |
1. Crystalline form of Pemetrexed Disodium which has characteristic reflexes in an X-ray powder diffractogram using CuKα radiation with Cukβ filter at a 2θ angle: 7.7±0.2, 9.7±0.2, 18.6±0.2, 19.2±0.2, 20.4±0.2, 24.3±0.2, 26.6±0.2, 28.7±0.2, 28.9±0.2, and 30.0±0.2. |
地址 |
Schaffhausen CH |