发明名称 Crystalline form of pemetrexed disodium
摘要 The present invention relates to a new polymorphic or crystalline form of Pemetrexed Disodium, processes for its preparation and its use, in particular for the preparation of medicaments.
申请公布号 US9174991(B2) 申请公布日期 2015.11.03
申请号 US201013511723 申请日期 2010.11.24
申请人 Azad Pharmaceutical Ingredients AG;University of Zurich 发明人 Albrecht Uwe Jens;Helmboldt Hannes;Nikolaev Vsevolod Valerievich
分类号 C07D487/04;A61K31/519;A61P35/00 主分类号 C07D487/04
代理机构 Rothwell, Figg, Ernst & Manbeck, P.C. 代理人 Rothwell, Figg, Ernst & Manbeck, P.C.
主权项 1. Crystalline form of Pemetrexed Disodium which has characteristic reflexes in an X-ray powder diffractogram using CuKα radiation with Cukβ filter at a 2θ angle: 7.7±0.2, 9.7±0.2, 18.6±0.2, 19.2±0.2, 20.4±0.2, 24.3±0.2, 26.6±0.2, 28.7±0.2, 28.9±0.2, and 30.0±0.2.
地址 Schaffhausen CH