发明名称 COMPOSITION FOR PREVENTING OR TREATING SEPSIS OR SEPTIC SHOCK, COMPRISING ADK PROTEIN AS ACTIVE INGREDIENT
摘要 The present invention relates to a composition for preventing or treating sepsis or septic shock, the composition comprising, as an active ingredient, adenosine kinase (ADK) protein derived from Mycobacterium tuberculosis. The ADK protein derived from Mycobacterium tuberculosis, according to the present invention, has an effect of inhibiting the binding between LPS and cells due to binding with LPS, and has good therapeutic effects on sepsis, such as an increase in the survival rate of a sepsis animal model, inhibition of inflammatory response in the lung and of cell death in the spleen, etc.
申请公布号 WO2015163533(A1) 申请公布日期 2015.10.29
申请号 WO2014KR06028 申请日期 2014.07.04
申请人 KONKUK UNIVERSITY INDUSTRIAL COOPERATION CORP 发明人 PARK, YEONG MIN;JUNG, IN DUK;SHIN, SUNG JAE;PARK, JUNG HEE;LEE, SEUNG JUN;KANG, TAE HEUNG;SOH, BYOUNG YUL
分类号 A61K38/16;A61P11/00;A61P31/04 主分类号 A61K38/16
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