| 发明名称 |
METHOD FOR IMPROVING PROTEIN EXPRESSION, AND COMPOSITION FOR PROTEIN EXPRESSION |
| 摘要 |
The present invention provides a method for improving protein expression, and a composition for protein expression. The composition, which is for use in causing target protein expression, comprises mRNA that codes the target protein, and the protein-coding regions of at least 80% of the mRNA in the composition have, at the 3' end thereof, a sequence substantially comprising poly-A having a base length of 230-250. |
| 申请公布号 |
WO2015162930(A1) |
申请公布日期 |
2015.10.29 |
| 申请号 |
WO2015JP02208 |
申请日期 |
2015.04.23 |
| 申请人 |
MEDICAL INDUSTRY INNOVATION INSTITUTE |
发明人 |
ITAKA, KEIJI;KATAOKA, KAZUNORI;IKEGAMI, MASARU;UCHIDA, SATOSHI;UCHIDA, HIROKUNI;NAGATA, KAZUYA |
| 分类号 |
C12N15/09;A61K31/7105;A61K48/00;A61P25/00;A61P25/02;A61P43/00 |
主分类号 |
C12N15/09 |
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