SALIVARY INFLAMMATORY BIOMARKERS ASSOCIATED WITH GLYCEMIC CONTROL AND ORAL HEALTH

摘要

The present invention provides non-invasive diagnostic methods and kits for determining and/or monitoring oral health and glycemic control in subjects with Type 1 diabetes.

主权项

1. A method of monitoring glycemic control in a subject with Type 1 diabetes, comprising:
obtaining a saliva sample from the subject; determining a level of one or more cytokine and/or matrix metalloproteinase (MMP) in the saliva sample; and comparing the level of the one or more cytokine and/or MMP in the saliva sample to a reference value; wherein an elevated level of the one or more cytokine and/or MMP in the saliva sample compared to the reference value indicates that the subject has decreased glycemic control.