发明名称 |
Thiocarbon-protecting groups for RNA synthesis |
摘要 |
<p>Aspects of the invention include 2'-protected nucleoside monomers that are protected at the 2'-site with thiocarbon protecting groups. Thiocarbon protecting groups of interest include thiocarbonate, thionocarbonate, dithiocarbonate groups, as well as thionocarbamate protecting groups. Aspects of the invention further include nucleic acids that include the protecting groups of the invention, as well as methods of synthesizing nucleic acids using the protecting groups of the invention.</p> |
申请公布号 |
EP2476689(B1) |
申请公布日期 |
2015.10.21 |
申请号 |
EP20120163999 |
申请日期 |
2008.05.09 |
申请人 |
AGILENT TECHNOLOGIES, INC. |
发明人 |
DELLINGER, DOUGLAS J.;SIERZCHALA, AGNIESKA;TURNER, JOHN;MYERSON, JOEL;KUPIHAR, ZOLTAN;FERREIRA, FERNANDO;CARUTHERS, MARVIN H. |
分类号 |
C07H19/073;A61K31/7072;A61K31/7076;A61K31/7088;C07H19/16;C07H21/02 |
主分类号 |
C07H19/073 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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