| 发明名称 | Compositions and methods for vaccinating against HSV-2 | ||
| 摘要 | This invention relates to therapeutic polynucleotide compositions and methods for systemic immune activation which are effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune response in mammals. The polynucleotide compositions are particularly effective for protecting mammals from herpes simplex virus (HSV), such as HSV gD2 polypeptides. | ||
| 申请公布号 | US9161973(B2) | 申请公布日期 | 2015.10.20 |
| 申请号 | US201414460230 | 申请日期 | 2014.08.14 |
| 申请人 | Vical Incorporated;UNIVERSITY OF WASHINGTON | 发明人 | Vilalta Adrian;Margalith Michal;Dong Lichun;Koelle David M. |
| 分类号 | A61K39/245;C12N7/00;A61K39/39;C07K14/005;C12N15/117;A61K39/00 | 主分类号 | A61K39/245 |
| 代理机构 | Sughrue Mion, PLLC | 代理人 | Sughrue Mion, PLLC |
| 主权项 | 1. A method for raising an immune response to a herpes simplex virus infection in a vertebrate comprising administering to the vertebrate, an isolated polynucleotide comprising SEQ ID NO:9, wherein the polynucleotide is administered in an amount sufficient to elicit an immune response to the infection. | ||
| 地址 | San Diego CA US | ||